The company was founded by Alastair Hook in 1999. He started the brewery in a small lock-up on an industrial estate, before moving to the Greenwich Brewery, and then to a site on nearby Blackwall Lane in 2010. It was purchased by SABMiller in May 2015. As part of the agreements made with regulators before Anheuser-Busch InBev was allowed to acquire SABMiller in 2016, Meantime was sold to Asahi Breweries of Japan in October 2016. Brewing moved to Fuller's in May 2024.